Invention has freed the brain from its bodily constraints, leaving the imagination unencumbered to envision paths that lead to obtaining even our wildest dreams. Like a shark, the brain never stops swimming in thought (Leher, 2010), and as it seeks new discoveries, the brain’s architectural landscape becomes reshaped. Recent innovative tools capitalize on the brain’s adaptive malleability, blurring the separation between nervous and cyber systems and in effect creating a symbiotic relationship. It is this interconnection that will enable humans to thrive on other worlds.